Determinants of water proton T1 in blood serum

H. H. Raeymaekers; Dirk Borghys; H. Eisendrath

doi:10.1002/mrm.1910060209

Determinants of water proton T₁ in blood serum

H. H. Raeymaekers
, Dirk Borghys
, H. Eisendrath

Applied Crypto Expertise

VUB University

Onderzoeksoutput: Bijdrage aan een tijdschrift › Opmerking/debat

17 Citaten (Scopus)

Samenvatting

Water proton T₁ (10.7 MHz; 7°C) and albumin and globulin contents were measured in the blood serum of 30 normal volunteers. The T₁ relaxivity of serum albumin and globulin (i.e., the change of water relaxation rate l/T₁ per concentration unit) was determined in pure albumin and globulin solutions. It is shown that more than 90% of the serum relaxation rate 1/T_l is due to the proteins, making T₁ a nonspecific blood parameter. In addition five pathological serum samples were examined, explaining clearly why serum T₁is not a clinically useful measurement. © 1988 Academic Press, Inc.

Originele taal-2	Engels
Pagina's (van-tot)	212-216
Aantal pagina's	5
Tijdschrift	Magnetic Resonance in Medicine
Volume	6
Nummer van het tijdschrift	2
DOI's	https://doi.org/10.1002/mrm.1910060209
Status	Gepubliceerd - feb. 1988

Toegang tot document

10.1002/mrm.1910060209

Andere bestanden en links

Link naar publicatie in Scopus

Citeer dit

@article{248f7beb419a455abe64bc6601ed0b89,

title = "Determinants of water proton T1 in blood serum",

abstract = "Water proton T1 (10.7 MHz; 7°C) and albumin and globulin contents were measured in the blood serum of 30 normal volunteers. The T1 relaxivity of serum albumin and globulin (i.e., the change of water relaxation rate l/T1 per concentration unit) was determined in pure albumin and globulin solutions. It is shown that more than 90\% of the serum relaxation rate 1/Tl is due to the proteins, making T1 a nonspecific blood parameter. In addition five pathological serum samples were examined, explaining clearly why serum T1is not a clinically useful measurement. {\textcopyright} 1988 Academic Press, Inc.",

author = "Raeymaekers, \{H. H.\} and Dirk Borghys and H. Eisendrath",

year = "1988",

month = feb,

doi = "10.1002/mrm.1910060209",

language = "English",

volume = "6",

pages = "212--216",

journal = "Magnetic Resonance in Medicine",

issn = "0740-3194",

number = "2",

}

TY - JOUR

T1 - Determinants of water proton T1 in blood serum

AU - Raeymaekers, H. H.

AU - Borghys, Dirk

AU - Eisendrath, H.

PY - 1988/2

Y1 - 1988/2

N2 - Water proton T1 (10.7 MHz; 7°C) and albumin and globulin contents were measured in the blood serum of 30 normal volunteers. The T1 relaxivity of serum albumin and globulin (i.e., the change of water relaxation rate l/T1 per concentration unit) was determined in pure albumin and globulin solutions. It is shown that more than 90% of the serum relaxation rate 1/Tl is due to the proteins, making T1 a nonspecific blood parameter. In addition five pathological serum samples were examined, explaining clearly why serum T1is not a clinically useful measurement. © 1988 Academic Press, Inc.

AB - Water proton T1 (10.7 MHz; 7°C) and albumin and globulin contents were measured in the blood serum of 30 normal volunteers. The T1 relaxivity of serum albumin and globulin (i.e., the change of water relaxation rate l/T1 per concentration unit) was determined in pure albumin and globulin solutions. It is shown that more than 90% of the serum relaxation rate 1/Tl is due to the proteins, making T1 a nonspecific blood parameter. In addition five pathological serum samples were examined, explaining clearly why serum T1is not a clinically useful measurement. © 1988 Academic Press, Inc.

UR - https://www.scopus.com/pages/publications/0023837620

U2 - 10.1002/mrm.1910060209

DO - 10.1002/mrm.1910060209

M3 - Comment/debate

C2 - 2835571

AN - SCOPUS:0023837620

SN - 0740-3194

VL - 6

SP - 212

EP - 216

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

IS - 2

ER -