Bacteriophage production in compliance with regulatory requirements

Jean Paul Pirnay, Maia Merabishvili, Hilde Van Raemdonck, Daniel De Vos, Gilbert Verbeken

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureHoofdstukpeer review

Samenvatting

In this chapter we review bacteriophage production requirements to help institutions, which wish to manufacture bacteriophage products for human use in compliance with the applicable regulatory expectancies, defining production processes and implementing relevant controls ensuring quality, safety, and efficacy of the final products. The information disclosed in this chapter can also serve as a basis for discussions with competent authorities regarding the development of expedited bacteriophage product development and licensing pathways, including relevant and pragmatic requirements, and allowing for the full exploitation of bacteriophages as natural controllers of bacterial populations.

Originele taal-2Engels
TitelMethods in Molecular Biology
UitgeverijHumana Press Inc.
Pagina's233-252
Aantal pagina's20
DOI's
StatusGepubliceerd - 2018

Publicatie series

NaamMethods in Molecular Biology
Volume1693
ISSN van geprinte versie1064-3745

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