Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo

Elene Kakabadze; Khatuna Makalatia; Nino Grdzelishvili; Nata Bakuradze; Marina Goderdzishvili; Ia Kusradze; Marie France Phoba; Octavie Lunguya; Cédric Lood; Rob Lavigne; Jan Jacobs; Stijn Deborggraeve; Tessa De Block; Sandra Van Puyvelde; David Lee; Aidan Coffey; Anahit Sedrakyan; Patrick Soentjens; Daniel De Vos; Jean Paul Pirnay; Nina Chanishvili

doi:10.3390/v10040172

Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo

Elene Kakabadze, Khatuna Makalatia, Nino Grdzelishvili, Nata Bakuradze, Marina Goderdzishvili, Ia Kusradze, Marie France Phoba, Octavie Lunguya, Cédric Lood, Rob Lavigne, Jan Jacobs, Stijn Deborggraeve, Tessa De Block, Sandra Van Puyvelde, David Lee, Aidan Coffey, Anahit Sedrakyan, Patrick Soentjens, Daniel De Vos, Jean Paul PirnayNina Chanishvili

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

Recently, a Salmonella Typhi isolate producing CTX-M-15 extended spectrum β-lactamase (ESBL) and with decreased ciprofloxacin susceptibility was isolated in the Democratic Republic of the Congo. We have selected bacteriophages that show strong lytic activity against this isolate and have potential for phage-based treatment of S. Typhi, and Salmonella in general.

langue originale	Anglais
Numéro d'article	172
journal	Viruses
Volume	10
Numéro de publication	4
Les DOIs	https://doi.org/10.3390/v10040172
état	Publié - avr. 2018

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10.3390/v10040172

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Contient cette citation

Kakabadze, E., Makalatia, K., Grdzelishvili, N., Bakuradze, N., Goderdzishvili, M., Kusradze, I., Phoba, M. F., Lunguya, O., Lood, C., Lavigne, R., Jacobs, J., Deborggraeve, S., De Block, T., Van Puyvelde, S., Lee, D., Coffey, A., Sedrakyan, A., Soentjens, P., De Vos, D., ... Chanishvili, N. (2018). Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo. Viruses, 10(4), Article 172. https://doi.org/10.3390/v10040172

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title = "Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo",

abstract = "Recently, a Salmonella Typhi isolate producing CTX-M-15 extended spectrum β-lactamase (ESBL) and with decreased ciprofloxacin susceptibility was isolated in the Democratic Republic of the Congo. We have selected bacteriophages that show strong lytic activity against this isolate and have potential for phage-based treatment of S. Typhi, and Salmonella in general.",

keywords = "Bacteriophages, Democratic republic of the Congo, Extended-spectrum beta lactamases (ESBL), Salmonella typhi, Typhoid fever",

author = "Elene Kakabadze and Khatuna Makalatia and Nino Grdzelishvili and Nata Bakuradze and Marina Goderdzishvili and Ia Kusradze and Phoba, {Marie France} and Octavie Lunguya and C{\'e}dric Lood and Rob Lavigne and Jan Jacobs and Stijn Deborggraeve and {De Block}, Tessa and {Van Puyvelde}, Sandra and David Lee and Aidan Coffey and Anahit Sedrakyan and Patrick Soentjens and {De Vos}, Daniel and Pirnay, {Jean Paul} and Nina Chanishvili",

note = "Publisher Copyright: {\textcopyright} 2018 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2018",

month = apr,

doi = "10.3390/v10040172",

language = "English",

volume = "10",

journal = "Viruses",

issn = "1999-4915",

number = "4",

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Kakabadze, E, Makalatia, K, Grdzelishvili, N, Bakuradze, N, Goderdzishvili, M, Kusradze, I, Phoba, MF, Lunguya, O, Lood, C, Lavigne, R, Jacobs, J, Deborggraeve, S, De Block, T, Van Puyvelde, S, Lee, D, Coffey, A, Sedrakyan, A, Soentjens, P, De Vos, D, Pirnay, JP & Chanishvili, N 2018, 'Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo', Viruses, VOL. 10, Numéro 4, 172. https://doi.org/10.3390/v10040172

Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo. / Kakabadze, Elene; Makalatia, Khatuna; Grdzelishvili, Nino et al.
Dans: Viruses, Vol 10, Numéro 4, 172, 04.2018.

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

TY - JOUR

T1 - Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo

AU - Kakabadze, Elene

AU - Makalatia, Khatuna

AU - Grdzelishvili, Nino

AU - Bakuradze, Nata

AU - Goderdzishvili, Marina

AU - Kusradze, Ia

AU - Phoba, Marie France

AU - Lunguya, Octavie

AU - Lood, Cédric

AU - Lavigne, Rob

AU - Jacobs, Jan

AU - Deborggraeve, Stijn

AU - De Block, Tessa

AU - Van Puyvelde, Sandra

AU - Lee, David

AU - Coffey, Aidan

AU - Sedrakyan, Anahit

AU - Soentjens, Patrick

AU - De Vos, Daniel

AU - Pirnay, Jean Paul

AU - Chanishvili, Nina

PY - 2018/4

Y1 - 2018/4

N2 - Recently, a Salmonella Typhi isolate producing CTX-M-15 extended spectrum β-lactamase (ESBL) and with decreased ciprofloxacin susceptibility was isolated in the Democratic Republic of the Congo. We have selected bacteriophages that show strong lytic activity against this isolate and have potential for phage-based treatment of S. Typhi, and Salmonella in general.

AB - Recently, a Salmonella Typhi isolate producing CTX-M-15 extended spectrum β-lactamase (ESBL) and with decreased ciprofloxacin susceptibility was isolated in the Democratic Republic of the Congo. We have selected bacteriophages that show strong lytic activity against this isolate and have potential for phage-based treatment of S. Typhi, and Salmonella in general.

KW - Bacteriophages

KW - Democratic republic of the Congo

KW - Extended-spectrum beta lactamases (ESBL)

KW - Salmonella typhi

KW - Typhoid fever

UR - http://www.scopus.com/inward/record.url?scp=85045078860&partnerID=8YFLogxK

U2 - 10.3390/v10040172

DO - 10.3390/v10040172

M3 - Article

C2 - 29614013

AN - SCOPUS:85045078860

SN - 1999-4915

VL - 10

JO - Viruses

JF - Viruses

IS - 4

M1 - 172

ER -